Pe'er Lab homepage

Computational Biology · Columbia University
Pe'er Lab

We develop computational methods to understand high-throughput biological data. We build probabilistic models, machine-learning methods, and advanced data representations, creating new computational tools to study the dynamics of the microbiome, the evolution of cancer, and the organization of single-cell systems.

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What we study
All research →
Microbiome Dynamics
Personalized growth rates, contamination correction, pan-metagenomic graphs, and microbiome-based prediction across studies.
Representation & Geometric Learning
Decision trees, random forests, and phylogenetic inference built on non-Euclidean and other advanced representations of biological data.
Cancer Genomics & Single-cell
Metacell inference (SEACells), transcriptomic plasticity in metastasis, and tumor microenvironment analysis at single-cell resolution.
More
Additional and earlier directions, including population and human genetics, are described on the full research page.
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Latest work
Google Scholar →
Jiménez-Sánchez A, Persad S, Hayashi A … Pe'er I, Iacobuzio-Donahue CA, Pe'er D
Cancer ResearchApr 2026 · 86(7):1769–1796
Austin GI, Pe'er I, Korem T
Science AdvancesNov 2025 · 11(48):eadx6976
Austin GI, Brown Kav A, ElNaggar S … Pe'er I, Korem T
Nature MicrobiologyApr 2025 · 10(4):897–911
The team
Prof. Pe'er
IP
Principal Investigator · Professor of Computer Science & Systems Biology · Vice Chair of Computer Science
Personal page →
Current lab members
AT
PhD · CS
2023– · w/ Knowles
RA
PhD · CS
2023– · w/ Gursoy
JB
PhD · CS
2022– · w/ Gursoy
Alumni — Postdoctoral researchers
SC
2011–2015
Now Associate Professor, Hebrew University of Jerusalem
scarmilab.org →
YS
2008–2011
Now Associate Professor, Columbia University
Lab website →
VV
2010–2012
Now VP Computational Biology, Lab11 Therapeutics
LinkedIn →
Alumni — PhD graduates
SP
PhD 2024
Now Postdoctoral Researcher, Memorial Sloan Kettering
Profile →
RK
PhD 2024
Now Postdoctoral Researcher, Stanford University
LinkedIn →
PC
PhD 2025
Now Research Scientist, Meta
chlenski.com →
YL
PhD 2025
Now Lecturer in Data Science, Columbia University
Website →
JY
PhD 2021
Now Research Scientist, Harvard Medical School
Profile →
TJ
PhD 2021
Now Statistical Geneticist, Regeneron
LinkedIn →
AM
PhD 2020
Now Assistant Professor, Spelman College
Faculty page →
CP
PhD 2017
Now Data Scientist, National Institutes of Health
ResearchGate →
AG
PhD 2012
Now Associate Professor of Medicine, Harvard Medical School
gusevlab.org →
PP
PhD 2014
Now Professor of Statistical Genomics, University of Oxford
palamaralab.github.io →
AK
PhD 2014
Now Assistant Professor, Rutgers Medical School
Faculty page →
SP2
PhD 2014
Now Chief Data Scientist, Stanford Cancer Center
LinkedIn →
ND
PhD 2011
Now Associate Director, Bioinformatics, GlaxoSmithKline
LinkedIn →
EK
PhD 2010
Now Professor & Director, Icahn School of Medicine, Mt Sinai
Faculty page →
Get in touch
Join the team
Contact
Affiliation
Mailing address
Department of Computer Science
450 Computer Science Building, Mailcode 0401
Columbia University
500 W 120th St, New York, NY